TAP Trial at Hennepin

Trauma is the leading cause of death in those under the age of 45. The most common cause of preventable death after injury is bleeding. Kcentra® (or 4-factor prothrombin complex concentrate) is a FDA approved product that contains clotting factors. It is currently used to reverse the effects of medications given to “thin” the blood in patients, when such patients experience bleeding and/or require surgery. There is evidence that Kcentra® may reduce the chance of dying in injured patients who are not on blood-thinning medication. The Trauma And Prothrombin Complex Concentrate (TAP) Trial is a research trial to see whether Kcentra reduces the chances of people dying from their injuries because of blood loss. To learn more about the TAP Trial, visit the study's website at https://www.uab.edu/medicine/cis/tap-trial-at-hennepin