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Traumatic Brain Injury (TBI) & Cortical Spreading Depolarization (CSD)

cramer, Samuel

Key Researcher

LinkedIn Profile

Samuel Cramer, MD, PhD, is currently serving as the Chief Resident in Neurosurgery and the Co-Principal Investigator of the clinical trial for Cortical Spreading Depolarization (CSD) for patients who experience a severe traumatic brain injury.

He is wrapping up his final year of residency at the University of Minnesota (U of M) and will be joining Hennepin Healthcare afterward. Dr. Cramer completed his undergrad at the U of M. His strong interest in neuroscience, the nervous system, and helping folks with different neurological illnesses led him to further his education at the University of Minnesota for his degrees as a Doctor of Medicine (MD) and Doctor of Philosophy (PhD). His research focuses on exploring different diagnostic and interventional modalities for Traumatic Brain Injury (TBI).

Traumatic Brain Injury (TBI) & Cortical Spreading Depolarization (CSD)

Dr. Cramer’s research explores alternative diagnostic and interventional modalities for Traumatic Brain Injury (TBI). The overall aim of his research efforts is to understand the maladaptive responses of the brain to injury. These efforts are part of developing new treatments, which minimize secondary brain injury and improve recovery following a TBI.

Currently, he works with multiple collaborators to address these questions using a combination of tools including the use of in vivo optical imaging in humanely treated mouse models with TBI, non-invasive neuromodulation techniques in patients with mild TBI, and invasive neuromonitoring to monitor for cortical spreading depolarization following severe TBI.

Pub Med

https://www.ncbi.nlm.nih.gov/myncbi/1bk05Quyrywk5p/bibliography/public/

Links

https://restorativeneurotraumalab.org/

Affiliated Researchers

Dr. David Darrow, MD, MPH; Attending Neurosurgeon at the University of Minnesota; Rockswold-Kaplan Endowed Chair for Traumatic Brain Injury at HCMC; and Director of the Restorative Neurotrauma Lab (RNL) at the Hennepin Healthcare Research Institute.  Restorative Neurotrauma Lab

Dr. Timothy Ebner, MD, PhD; Department Head and Professor, Department of Neuroscience in the Graduate Program at the University of Minnesota.

Links

https://med.umn.edu/neurosurgery/faculty

cramer, Samuel

Key Researcher

Samuel Cramer, MD, PhD, is currently serving as the Chief Resident in Neurosurgery and the Co-Principal Investigator of the clinical trial for Cortical Spreading Depolarization (CSD) following a severe traumatic brain injury.

He is wrapping up his final year of residency at the University of Minnesota and will be joining Hennepin Healthcare afterward. Dr. Cramer completed his undergrad at the University of Minnesota (U of M). His strong interest in neuroscience, the nervous system, and helping folks with different neurological illnesses led him to further his education at the U of M for his degrees as a Doctor of Medicine (MD) and Doctor of Philosophy (PhD). His research focuses on exploring different diagnostic and interventional modalities for Traumatic Brain Injury (TBI).

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