
Key Researcher
Matthew Prekker, MD, MDH, is an Associate Professor of Medicine and Emergency Medicine at the University of Minnesota Medical School.
Dr. Prekker cares for critically ill patients at Hennepin Healthcare in the Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Emergency Medicine. In this role, he directs the Extracorporeal Life Support Program at Hennepin County Medical Center. He’s board certified in Emergency Medicine, Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. He attended the University of Minnesota Medical School for his Doctorate of Medicine (MD) and the University of Minnesota School of Public Health for his Master of Public Health (MPH) degree, then completed the combined Emergency and Internal Medicine residency at Hennepin followed by a Pulmonary and Critical Care Medicine (PCCM) fellowship at the University of Washington-Seattle.
Emergency Medicine, Pulmonary, and Critical Care
In Dr. Prekker’s day-to-day work, he frequently performs emergency tracheal intubation and teaches the procedure to residents and fellows. While challenging, he hopes to use this broad experience to integrate research into the practice of emergency tracheal intubation in the Emergency Department (ED) and Intensive Care Unit (ICU).
He’s previously collaborated with Dr. Brian Driver’s team to understand the processes of clinical care at Hennepin to efficiently and safely integrate rigorous randomized trials into clinical care during this emergency procedure. These collaborations have produced three of the largest and most rigorous trials of airway management ever conducted. With this nationwide research network and collaboration with Dr. Driver, he plans additional pragmatic, multicenter trials on emergency intubation.
Links
https://www.pragmaticcriticalcare.org/
https://pubmed.ncbi.nlm.nih.gov/34879143/
https://pubmed.ncbi.nlm.nih.gov/35707974/
https://criticalcarereviews.com/meetings/ccr23
https://classic.clinicaltrials.gov/ct2/show/NCT05239195
Honors
2020 Platinum Center of Excellence, The Extracorporeal Life Support Organization
2017 Alpha Omega Alpha faculty inductee, Senior Medical Students at U of MN
2015 Semi-Finalist, Young Investigator Award, SAEM Annual Meeting
2014 Best Faculty Didactic Presentation, HCMC Department of Emergency Medicine
Publications
Prekker ME, Driver, BE, Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults. NEJM 2023; doi:10.1056/NEJMoa2301601
Prekker ME, Feemster LC, Hough CL, et al. The epidemiology and outcome of prehospital respiratory distress. Acad Emerg Med 2014; 21(5):543–50. doi: https://doi.org/10.1111/acem.12380
Prekker ME, Kwok H, Shin J, Carlbom D, Grabinsky A, Rea TD. The process of prehospital airway management: challenges and solutions during paramedic endotracheal intubation. Crit Care Med 2014; 42(6):1372–8.
Prekker ME, Delgado F, Shin J, et al. Pediatric Intubation by Paramedics in a Large Emergency Medical Services System: Process, Challenges, and Outcomes. Ann Emerg Med 2016; 67(1):20–9 e4.
Driver B, Dodd K, Klein LR, Buckley R, Robinson A, McGill JW, Reardon RF, Prekker ME. The Bougie and First-Pass Success in the Emergency Department. Ann Emerg Med 2017; 70(4):473–8.e1.
Driver BE, Prekker ME, Klein LR, et al. Effect of Use of a Bougie vs Endotracheal Tube and Stylet on First-Attempt Intubation Success Among Patients With Difficult Airways Undergoing Emergency Intubation: A Randomized Clinical Trial. JAMA 2018; 319(21):2179–89.
Driver BE, Klein LR, Carlson K, Harrington J, Reardon RF, Prekker ME. Preoxygenation With Flush Rate Oxygen: Comparing the Nonrebreather Mask With the Bag-Valve Mask. Ann Emerg Med 2018;71(3):381–6.
Prekker ME, Donelan C, Ambur S, et al. Adoption of low tidal volume ventilation in the emergency department: A quality improvement intervention. Am J Emerg Med 2020;38(4):763–7.
Cole JB, Olives TD, Ulici A, Litell JM, Bangh SA, Arens AM, Puskarich MA, Prekker ME. Extracorporeal Membrane Oxygenation for Poisonings Reported to U.S. Poison Centers from 2000 to 2018: An Analysis of the National Poison Data System. Crit Care Med 2020;48(8):1111–9.
Prekker ME, Brunsvold ME, Bohman JK, et al. Regional Planning for Extracorporeal Membrane Oxygenation Allocation During Coronavirus Disease 2019. Chest 2020;158(2):603–7.
Calcaterra D, Heather B, Kohl LP, Erickson HL, Prekker ME. Bedside veno-venous ECMO cannulation: A pertinent strategy during the COVID-19 pandemic. J Card Surg 2020;35(6):1180–5.
Driver BE, Prekker ME, Levitan RM, et al. Engagement of the Median Glossoepiglottic Fold and Laryngeal View During Emergency Department Intubation. Ann Emerg Med [Internet] 2021; Available from: http://dx.doi.org/10.1016/j.annemergmed.2021.04.024.

Key Researcher
Matthew Prekker, MD, MDH, is an Associate Professor of Medicine and Emergency Medicine at the University of Minnesota Medical School.
Dr. Prekker cares for critically ill patients at Hennepin Healthcare in the Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Emergency Medicine. In this role, he directs the Extracorporeal Life Support Program at Hennepin County Medical Center. He’s board certified in Emergency Medicine, Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. He attended the University of Minnesota Medical School for his Doctorate of Medicine (MD) and the University of Minnesota School of Public Health for his Master of Public Health (MPH) degree, then completed the combined Emergency and Internal Medicine residency at Hennepin followed by a Pulmonary and Critical Care Medicine (PCCM) fellowship at the University of Washington-Seattle.