Respiratory Pathogen Immunity, Vaccination, and Treatment
Hennepin Healthcare has been a key collaborator in national networks to understand the prevention and treatment of SARS-CoV-2. In addition, our laboratory has coordinated the recruitment and immunoprofiling for an NIH funded study to study cardiac complications of this infection.
Key Publications
Raglow Z, Surie D, Chappell JD, Zhu Y, Martin ET, Kwon JH, Frosch AE, Mohamed A, Gilbert J, Bendall EE, Bahr A, Halasa N, Talbot HK, Grijalva CG, Baughman A, Womack KN, Johnson C, Swan SA, Koumans E, McMorrow ML, Harcourt JL, Atherton LJ, Burroughs A, Thornburg NJ, Self WH, Lauring AS. SARS-CoV-2 shedding and evolution in patients who were immunocompromised during the omicron period: a multicentre, prospective analysis. Lancet Microbe. 2024 Mar;5(3):e235-e246. doi: 10.1016/S2666-5247(23)00336-1. Epub 2024 Jan 26. PubMed PMID: 38286131.
Zhang W, Huang L, Ye G, Geng Q, Ikeogu N, Harris M, Dileepan G, Burrack K, Du L, Frosch A, Li F. Vaccine booster efficiently inhibits entry of SARS-CoV-2 omicron variant. Cell Mol Immunol. 2022 Mar;19(3):445-446. doi: 10.1038/s41423-022-00837-6. Epub 2022 Jan 24. PubMed PMID: 35075267; PubMed Central PMCID: PMC8785151.
Linderman SL, Lai L, Bocangel Gamarra EL, Lau MS, Edupuganti S, Surie D, Tenforde MW, Chappell JD, Mohr NM, Gibbs KW, Steingrub JS, Exline MC, Shapiro NI, Frosch AE, Qadir N, Davis-Gardner ME, McElrath MJ, Lauring AS, Suthar MS, Patel MM, Self WH, Ahmed R. Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection. J Clin Invest. 2022 Dec 1;132(23). doi: 10.1172/JCI164303. PubMed PMID: 36256473; PubMed Central PMCID: PMC9711871.
Adams K, Rhoads JP, Surie D, Gaglani M, Ginde AA, McNeal T, Talbot HK, Casey JD, Zepeski A, Shapiro NI, Gibbs KW, Files DC, Hager DN, Frosch AE, Exline MC, Mohamed A, Johnson NJ, Steingrub JS, Peltan ID, Brown SM, Martin ET, Lauring AS, Khan A, Busse LW, Duggal A, Wilson JG, Chang SY, Mallow C, Kwon JH, Chappell JD, Halasa N, Grijalva CG, Lindsell CJ, Lester SN, Thornburg NJ, Park S, McMorrow ML, Patel MM, Tenforde MW, Self WH. Vaccine effectiveness of primary series and booster doses against covid-19 associated hospital admissions in the United States: living test negative design study. BMJ. 2022 Oct 11;379:e072065. doi: 10.1136/bmj-2022-072065. PubMed PMID: 36220174; PubMed Central PMCID: PMC9551237.
Key Collaborators
