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Improving patient care and the health of our community through research and education

Transforming discoveries into better patient care

"Our patients at Hennepin Healthcare benefit from the research we do at the Hennepin Healthcare Research Institute by getting access to newer medications and new treatments that are available through our research programs."

~ Ajay Israni, MD
Hennepin Healthcare Research Institute President

Research Areas

At the Hennepin Healthcare Research Institute (HHRI), we've been investigating the causes of and potential treatments for diseases since 1952. We support and oversee medical research at HCMC, Hennepin Healthcare's acute care and teaching hospital.  Our research topics are diverse with a focus on four areas: Acute Care/Trauma, Addiction, Health Services and Infectious Diseases (HIV/AIDS). Innovative discoveries made at HHRI improve the lives of patients in our local community and across the globe.

HHRI Research Highlights

Statewide research program to address impact of racism on cardiovascular health inequities

October 19, 2021

People in Minnesota’s Black, Indigenous and communities of color experience some of the worst health disparities in the United States. A new research center, the Center for Chronic Disease Reduction and Equity Promotion Across Minnesota (C2DREAM), led by the University of Minnesota (U of M) and Mayo Clinic, will research the impact of structural and interpersonal racism…

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Dr. Winkelman talks about EHR Consortium and COVID-19 on Healthy Matters on WCCO radio

September 28, 2021

Hennepin Healthcare physician and HHRI researcher Dr. Tyler Winkelman was Dr. David Hilden’s guest Healthy Matters on WCCO 830-AM radio on Sunday, September 26, talking about the Electronic Health Records (EHR) Consortium, COVID-19 vaccinations and stats, health equity, and how Minnesota collaborates. Dr. Winkelman leads the Minnesota consortium. Their mission is to improve health by informing policy and practice…

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Embedding Human-Centered Design and LHS Research in the Transplantation System

September 23, 2021

Cory Schaffhausen, PhD, a Hennepin Healthcare Research Institute (HHRI) investigator, was recently featured in the University of Minnesota School of Public Health news where he discussed using the Learning Health System (LHS) model to design a tool to support the organ transplant decision process. Dr. Schaffhausen stated that the current process for matching an organ…

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