Improving patient care and the health of our community through research and education

Transforming discoveries into better patient care

"Our patients at Hennepin Healthcare benefit from the research we do at the Hennepin Healthcare Research Institute by getting access to newer medications and new treatments that are available through our research programs."

~ Ajay Israni, MD
Hennepin Healthcare Research Institute Interim President

Research Areas

At the Hennepin Healthcare Research Institute (HHRI), we've been investigating the causes of and potential treatments for diseases since 1952. We support and oversee medical research at HCMC, Hennepin Healthcare's acute care and teaching hospital.  Our research topics are diverse with a focus on four areas: Acute Care/Trauma, Addiction, Health Services and Infectious Diseases (HIV/AIDS). Innovative discoveries made at HHRI improve the lives of patients in our local community and across the globe.

HHRI Research Highlights

HHRI researchers awarded NIH HEAL Initiative funding to tackle the nation’s opioid crisis

October 29, 2019

The Helping to End Addiction Long-term Initiative, or NIH HEAL Initiative, is an aggressive, trans-agency effort to accelerate scientific solutions to stop the nation’s opioid crisis. Its research focus is on improving prevention and treatment for opioid misuse and addiction and enhancing pain management. HHRI investigators across disciplines are at the forefront in addressing this…

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ASPREE-XT (eXTension) study receives $42.3 million to determine longer-term effects of aspirin on health

July 31, 2019

The ASPREE-XT (eXTension)* study was recently awarded $42.3 million in funding from the National Institute On Aging of the National Institutes of Health (NIH). The five-year grant enables researchers to study if there are possible long-term health benefits of being on low-dose aspirin. ASPREE-XT is led by the Berman Center for Outcomes and Clinical Research…

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Study shows trust is an important attribute to clinician satisfaction; identifies characteristics associated with gender, organizational climate

June 21, 2019

There is a new emphasis on clinician trust in healthcare organizations, but little data about how to build trust and what favorable outcomes might result from doing so. In a prospective study of data collected as part of a randomized control trial, researchers used a previously validated measure to assess trust in 165 physicians and…

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General Research News

Image of Kidneys

Administration announces bold plan to transform kidney care

On July 10, 2019, the President of the United States signed an Executive Order to launch Advancing American Kidney Health, a comprehensive initiative to improve the lives of Americans suffering from kidney disease, the ninth-leading cause of death in the United States. The robust plan provides specific solutions to deliver on three goals: fewer patients developing kidney failure, fewer Americans receiving dialysis in dialysis centers, and more kidneys available for transplant.
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